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Anti-VPS54 Antibody

Boster Bio Anti-VPS54 Antibody catalog # A07056. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Vacuolar protein sorting-associated protein 54; Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p; VPS54; HCC8

Gene Name

VPS54

UniProt

Q9P1Q0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human VPS54 (NP_001005739.1) .

Clonality

Polyclonal

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN) . The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:18367545) . Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling (PubMed:25799061) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

110589 MW

Gene Name Synonym

Vacuolar protein sorting-associated protein 54

Subcellular Location

Golgi apparatus, trans-Golgi network

Protein Name

Vacuolar protein sorting-associated protein 54

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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