Anti-TRIP13 (E121) Antibody
Boster Bio Anti-TRIP13 (E121) Antibody catalog # A06921. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Pachytene checkpoint protein 2 homolog; Human papillomavirus type 16 E1 protein-binding protein;16E1-BP; HPV16 E1 protein-binding protein; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13; TRIP13; PCH2
Gene Name
TRIP13
UniProt
Q15645
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 91-151 of Human TRIP13.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity) . Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
48551 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Pachytene checkpoint protein 2 homolog
Protein Name
Pachytene checkpoint protein 2 homolog
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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