Anti-DP-2 TFDP2 Antibody
Boster Bio Anti-DP-2 TFDP2 Antibody catalog # A06850. Tested in WB, ELISA applications. This antibody reacts with Human, Monkey, Mouse, Rat.
Product Specifications
Synonyms
Transcription factor Dp-2; E2F dimerization partner 2; TFDP2; DP2
Gene Name
TFDP2
UniProt
Q14188
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human DP-2. AA range:64-113
Tissue Specificity
High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
49236 MW
Gene Name Synonym
Transcription factor Dp-2
Subcellular Location
Nucleus.
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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