Anti-Sam50/SAMM50 Antibody
Boster Bio Anti-Sam50/SAMM50 Antibody catalog # A06847-1. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Sam50, encoded by the SAMM50 gene, is an essential protein of the mitochondrial outer membrane (OMM) . It contains a beta-barrel domain conserved from bacteria to man (PMID: 14570913) . Sam50 is a part of the sorting and assembly machinery (SAM) necessary for the assembly of beta-barrel proteins in the OMM (PMID: 22252321) . It is crucial for maintaining mitochondrial shape, morphology of mitochondrial cristae, and assembly of the mitochondrial respiratory chain complexes (PMID: 26587038; 22252321; 25781180) . Polymorphisms in the SAMM50 gene have been associated with development and progression of nonalcoholic fatty liver disease (PMID: 23535911) .
Synonyms
SAMM50; TOB55; SAMM 50; OMP85; CGI-51
Gene Name
SAMM50
UniProt
Q9Y512
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human Sam50/SAMM50 recombinant protein (Position: T3-F199) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
SAMM50 sorting and assembly machinery component
Protein Name
Sorting and assembly machinery component 50 homolog
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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