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Anti-PACS-1 Antibody

Boster Bio Anti-PACS-1 Antibody (Catalog# A06811) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Phosphofurin acidic cluster sorting protein 1; PACS-1; PACS1; KIAA1175

Gene Name

PACS1

UniProt

Q6VY07

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant PACS-1 protein (amino acids 150-400)

Clonality

Polyclonal

Applications

WB

Field of Research

Coat Proteins, Golgi Proteins, Host-Virus Interaction, Interspecies Interaction, Metabolism, Microbiology, Obesity, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin- coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

104898 MW

Applications Notes

Western blot: 1-3 μg/ml

Gene Name Synonym

Phosphofurin acidic cluster sorting protein 1

Subcellular Location

Golgi apparatus, trans-Golgi network. Localizes in the perinuclear region, probably the TGN.

Protein Name

Phosphofurin acidic cluster sorting protein 1

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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