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Anti-Nexilin/NEXN Antibody

Boster Bio Anti-Nexilin/NEXN Antibody catalog # A06648-1. Tested in WB, IHC, IF, ELISA. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Nexilin, Also known as NEXN, NELIN, is a filamentous actin-binding protein that localizes to focal contacts and may be involved in cell adhesion and migration (PMID: 15823560) . Nexilin is abundantly expressed in heart and skeletal muscle and has an essential role in the maintenance of Z line and sarcomere integrity (PMID: 12053183, 19881492) . Mutations in Nexilin have been associated with cardiomyopathy dilated type 1CC (CMD1CC) and cardiomyopathy familial hypertrophic type 20 (CMH20) (PMID: 19881492, 20970104) .

Gene Name

NEXN

UniProt

Q0ZGT2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human Nexilin/NEXN recombinant protein (Position: K111-P358) .

Clonality

Polyclonal

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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