Anti-CLEC2D Antibody

Boster Bio Anti-CLEC2D Antibody catalog # A06635-1. Tested in WB, ELISA applications. This antibody reacts with Human.

Product Specifications

Background

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741) . Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700) . CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512) . It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786) .

Gene Name

CLEC2D

UniProt

Q9UHP7

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human CLEC2D recombinant protein (Position: D3-W151) .

Clonality

Polyclonal

Applications

WB, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.