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Anti-PRAME Antibody

Boster Bio Anti-PRAME Antibody catalog # A06628. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Melanoma antigen preferentially expressed in tumors ; Opa-interacting protein 4; OIP-4; Preferentially expressed antigen of melanoma; PRAME

Gene Name

PRAME

UniProt

P78395

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PRAME (NP_006106.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed in testis. Detected in samples of kidney, brain and skin.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

57890 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Melanoma antigen preferentially expressed in tumors

Subcellular Location

Nucleus

Protein Name

Melanoma antigen preferentially expressed in tumors

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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