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Anti-TBX4 Antibody (N-term)

Boster Bio Anti-TBX4 Antibody (N-term) (Catalog # A06607) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.

Synonyms

T-box transcription factor TBX4, T-box protein 4, TBX4

Gene Name

TBX4

UniProt

P57082

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the N-terminal region of human TBX4.

Clonality

Polyclonal

Applications

WB

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Transcriptional regulator that has an essential role in the organogenesis of lungs, pelvis, and hindlimbs.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

60204 Da

Applications Notes

WB: 1:1000

Subcellular Location

Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.

Prediction Reactivity

Chicken, Rat, Xenopus

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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