Anti-NR2C1 Antibody
Boster Bio Anti-NR2C1 Antibody catalog # A06568. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor TR2; Testicular receptor 2; NR2C1; TR2
Gene Name
NR2C1
UniProt
P13056
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human NR2C1 (NP_003288.2) .
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid- regulated preadipocyte proliferation.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
67315 MW
Gene Name Synonym
Nuclear receptor subfamily 2 group C member 1
Subcellular Location
Nucleus
Protein Name
Nuclear receptor subfamily 2 group C member 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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