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Anti-STAM2 (phospho-Y192) Antibody

Boster Bio Anti-STAM2 (phospho-Y192) Antibody catalog # A06533Y192. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein; STAM2; HBP

Gene Name

STAM2

UniProt

O75886

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human STAM2 around the phosphorylation site of Tyrosine 192.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex) . The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

58164 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Signal transducing adapter molecule 2

Subcellular Location

Cytoplasm . Early endosome membrane

Protein Name

Signal transducing adapter molecule 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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