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Anti-MCCC2 Antibody (Center)

Boster Bio Anti-MCCC2 Antibody (Center) (Catalog # A06515-1) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human, Rat.

Product Specifications

Background

MCCC2 is the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA.

Synonyms

Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, MCCase subunit beta, 3-methylcrotonyl-CoA carboxylase 2, 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta, MCCC2, MCCB

Gene Name

MCCC2

UniProt

Q9HCC0

Host

Rabbit

Reactivity

Human, Rat

Immunogen

This MCCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-189 amino acids from the Central region of human MCCC2.

Clonality

Polyclonal

Applications

WB, IHC-P, Flow Cytometry

Field of Research

Metabolism, Signal Transduction, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

61333 Da

Subcellular Location

Mitochondrion matrix

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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