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Anti-MYSM1 Antibody

Boster Bio Anti-MYSM1 Antibody catalog # A06500. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Histone H2A deubiquitinase MYSM1;2A-DUB;3.4.19.-; Myb-like, SWIRM and MPN domain-containing protein 1; MYSM1; KIAA1915

Gene Name

MYSM1

UniProt

Q5VVJ2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MYSM1. AA range:520-569

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR) -induced gene activation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

95032 MW

Gene Name Synonym

Histone H2A deubiquitinase MYSM1

Subcellular Location

Nucleus .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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