Anti-MYSM1 Antibody
Boster Bio Anti-MYSM1 Antibody catalog # A06500. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Histone H2A deubiquitinase MYSM1;2A-DUB;3.4.19.-; Myb-like, SWIRM and MPN domain-containing protein 1; MYSM1; KIAA1915
Gene Name
MYSM1
UniProt
Q5VVJ2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MYSM1. AA range:520-569
Applications
WB, IHC, IF, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR) -induced gene activation. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
95032 MW
Gene Name Synonym
Histone H2A deubiquitinase MYSM1
Subcellular Location
Nucleus .
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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