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Anti-RECK Antibody

Boster Bio Anti-RECK Antibody (Catalog# A06439) . Tested in IHC, ICC, IF, WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein

Gene Name

RECK

UniProt

O95980

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human RECK. Immunogen sequence location: 21-70

Clonality

Polyclonal

Tissue Specificity

Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.

Applications

IHC, ICC, IF, WB, ELISA

Field of Research

Cancer, Cell Biology, Oncoproteins/Suppressors, Protease Inhibitors, Proteolysis/Ubiquitin, Tumor Suppressors

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

106457 MW

Gene Name Synonym

Reversion-inducing cysteine-rich protein with Kazal motifs

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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