Anti-ATPIF1/ATP5IF1 Antibody
Boster Bio Anti-ATPIF1/ATP5IF1 Antibody catalog # A06408-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human.
Product Specifications
Background
The H (+) -ATP synthase is a reversible engine of mitochondria that synthesizes or hydrolyzes ATP upon changes in cell physiology. ATP synthase dysfunction is involved in the onset and progression of diverse human pathologies. ATPIF1 gene encodes mitochondrial ATPase Inhibitory Factor 1 (IF1), also named ATPI, ATPIP or IP. Endogenous IF1 limits ATP depletion when the mitochondrial membrane potential falls below a threshold and the ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Mitochondrial content of IF1 controls the activity of oxidative phosphorylation mediating the shift of cancer cells to an enhanced aerobic glycolysis, thus supporting an oncogenic role of IF1 in cancer.
Synonyms
IF (1) ; ATPIP; ATPI; ATPase inhibitory factor 1; ATP5IF1
Gene Name
ATP5IF1
UniProt
Q9UII2
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human ATPIF1/ATP5IF1 recombinant protein (Position: V3-H104) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
ATP synthase inhibitory factor subunit 1
Protein Name
ATPase inhibitor, mitochondrial
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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