Anti-USP30 Antibody
Boster Bio Anti-USP30 Antibody catalog # A06403-3. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
USP30, a mitochondrion-localized deubiquitylase, regulates mitophagy. Mitochondrial damage stimulates parkin to assemble Lys 6, Lys 11 and Lys 63 chains on mitochondria, and that USP30 is a ubiquitin-specific deubiquitylase with a strong preference for cleaving Lys 6- and Lys 11-linked multimers. USP30 can be ubiquitinated by parkin (PARK2) at Lys-235 and Lys-289. USP30 inhibition is potentially beneficial for treating Parkinson disease by promoting mitochondrial clearance and quality control. USP30 was detected 67 kDa by ubiquitination (PMID: 34704599) .
Synonyms
Ubiquitin-specific-processing protease 30; Ubiquitin thiolesterase 30; Ubiquitin thioesterase 30; Ubiquitin carboxyl-terminal hydrolase 30; EC:3.4.19.12
Gene Name
USP30
UniProt
Q70CQ3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human USP30 recombinant protein (Position: T161-S506) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Ubiquitin specific peptidase 30
Protein Name
Ubiquitin carboxyl-terminal hydrolase 30
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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