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Anti-LILRA3 Antibody (C-term)

Boster Bio Anti-LILRA3 Antibody (C-term) (Catalog # A06300) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

May act as soluble receptor for class I MHC antigens.

Synonyms

Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4

Gene Name

LILRA3

UniProt

Q8N6C8

Host

Rabbit

Reactivity

Human

Immunogen

This LILRA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human LILRA3.

Clonality

Polyclonal

Tissue Specificity

Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung

Applications

WB

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

47472 Da

Applications Notes

WB: 1:1000

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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