Anti-LILRA3 Antibody (C-term)
Boster Bio Anti-LILRA3 Antibody (C-term) (Catalog # A06300) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
May act as soluble receptor for class I MHC antigens.
Synonyms
Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4
Gene Name
LILRA3
UniProt
Q8N6C8
Host
Rabbit
Reactivity
Human
Immunogen
This LILRA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human LILRA3.
Clonality
Polyclonal
Tissue Specificity
Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung
Applications
WB
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
47472 Da
Applications Notes
WB: 1:1000
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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