Anti-RENALASE/RNLS Antibody
Boster Bio Anti-RENALASE/RNLS Antibody catalog # A06291-2. Tested in WB, IHC, IF, ICC, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
RNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity. (PMID:15841207) This antibody is specific to RNLS.
Synonyms
C10orf59; Monoamine oxidase-C; Monoamine oxidase C; MAO-C; MAO C
Gene Name
RNLS
UniProt
Q5VYX0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human RENALASE/RNLS recombinant protein (Position: Q3-N340) .
Clonality
Polyclonal
Applications
WB, IHC, IF, ICC, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Renalase, FAD dependent amine oxidase
Protein Name
Renalase
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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