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Anti-MTHFD1L Antibody

Boster Bio Anti-MTHFD1L Antibody catalog # A06289. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Monofunctional C1-tetrahydrofolate synthase, mitochondrial;6.3.4.3; Formyltetrahydrofolate synthetase; MTHFD1L; FTHFSDC1

Gene Name

MTHFD1L

UniProt

Q6UB35

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human MTHFD1L (NP_056255.2) .

Clonality

Polyclonal

Tissue Specificity

Detected in most tissues, highest expression found in placenta, thymus and brain. Low expression is found in liver and skeletal muscle. Up-regulated in colon adenocarcinoma.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

105790 MW

Gene Name Synonym

Monofunctional C1-tetrahydrofolate synthase, mitochondrial

Subcellular Location

Mitochondrion

Protein Name

Monofunctional C1-tetrahydrofolate synthase, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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