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Anti-ASH2L Antibody (Center)

Boster Bio Anti-ASH2L Antibody (Center) (Catalog # A06129) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Synonyms

Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L, ASH2L1

Gene Name

ASH2L

UniProt

Q9UBL3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ASH2L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 237-270 amino acids from the Central region of human ASH2L.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.

Applications

WB

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

12670868191313381955624519556245126708682122012022266653

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

68723 Da

Applications Notes

WB: 1:1000

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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