Anti-MaxiK beta KCNMB4 Antibody
Boster Bio Anti-MaxiK beta KCNMB4 Antibody catalog # A06117. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Calcium-activated potassium channel subunit beta-4; BK channel subunit beta-4; BKbeta4; Hbeta4; Calcium-activated potassium channel, subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; K (VCA) beta-4; Maxi K channel subunit beta-4; Slo-beta-4; KCNMB4
Gene Name
KCNMB4
UniProt
Q86W47
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MaxiKbeta. AA range:70-119
Tissue Specificity
Predominantly expressed in brain. In brain, it is expressed in the cerebellum, cerebral cortex, medulla, spinal cord, occipital pole, frontal lobe, temporal lobe, putamen, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Weakly or not expressed in other tissues. .
Applications
WB, IHC, IF, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
23949 MW
Gene Name Synonym
Calcium-activated potassium channel subunit beta-4
Subcellular Location
Membrane; Multi-pass membrane protein.
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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