Anti-ELK3 Antibody (N-term)
Boster Bio Anti-ELK3 Antibody (N-term) (Catalog # A06026) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
Synonyms
ETS domain-containing protein Elk-3, ETS-related protein ERP, ETS-related protein NET, Serum response factor accessory protein 2, SAP-2, SRF accessory protein 2, ELK3, NET, SAP2
Gene Name
ELK3
UniProt
P41970
Host
Rabbit
Reactivity
Human
Immunogen
This ELK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human ELK3.
Clonality
Polyclonal
Applications
WB
Field of Research
Immunology, Interleukins
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
44240 Da
Applications Notes
WB: 1:1000
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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