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Anti-CMRF35-like molecule 8 CD300a Antibody

Selected Variant

A05953

Size: 100 µL

Boster Bio Anti-CMRF35-like molecule 8 CD300a Antibody catalog # A05953. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CMRF35-like molecule 8; CLM-8; CD300 antigen-like family member A; CMRF-35-H9; CMRF35-H9; CMRF35-H; IRC1/IRC2; Immunoglobulin superfamily member 12; IgSF12; Inhibitory receptor protein 60; IRp60; NK inhibitory receptor; CD300a; CD300A; CMRF35H, IGSF12; HSPC083

Gene Name

CD300A

UniProt

Q9UGN4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from human protein at AA range: 141-190

Clonality

Polyclonal

Tissue Specificity

Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:10746781, PubMed:16339535, PubMed:9701027) . Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed:22043923) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

33201 MW

Gene Name Synonym

CMRF35-like molecule 8

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Protein Name

CMRF35-like molecule 8

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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