Anti-LHX2 Antibody

LHX proteins can activate or repress gene transcription by direct DNA binding and association with co-activators or co-repressors through their LIM domain. The LIM homeobox 2 (LHX2), also known as LH2, is a member of the LIM homeodomain family of proteins. LHX2 functions as a nuclear transcription co-factor and is reported to be involved in many important physiological processes, such as cell division, cell proliferation, specific cell-type differentiation, and cerebral cortex development. LHX2 promotes the growth and metastasis of nasopharyngeal carcinoma by regulating Wnt signaling and plays a vital role in breast cancer's progression and prognosis (PMID: 37345110) .