Anti-CASC3 Antibody
Boster Bio Anti-CASC3 Antibody catalog # A05890-1. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Background
CASC3 (cancer susceptibility candidate 3) is also named as MLN51 and belongs to the CASC3 family. It is induced by CSF2, and is important in the proliferation of RA fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis (RA) (PMID:17101062) . It is a nucleocytoplasmic protein containing, within its aminoterminal half, a coiled-coil domain followed by two nuclear localization signals (NLSs) responsible for nuclear localization and, in its carboxyl-terminal half, a nuclear export signal (NES) that mediates cytoplasmic retention. It possesses many potential phosphorylation sites and is found to be phosphorylated in both normal and cancer-derived cells. (PMID:17652158) .
Synonyms
CASC3; MLN51; MLN 51; CASC 3; Btz
Gene Name
CASC3
UniProt
O15234
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human CASC3 recombinant protein (Position: Q356-G701) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
CASC3 exon junction complex subunit
Protein Name
Protein CASC3
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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