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Anti-SRSF7 (N103) Antibody

Boster Bio Anti-SRSF7 (N103) Antibody catalog # A05827. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Serine/arginine-rich splicing factor 7; Splicing factor 9G8; Splicing factor, arginine/serine-rich 7; SRSF7; SFRS7

Gene Name

SRSF7

UniProt

Q16629

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 71-122 of Human SRSF7.

Clonality

Polyclonal

Tissue Specificity

Brain, liver, kidney and lung.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway) ; enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

27367 MW

Applications Notes

IHC: 1:50-1:200

Gene Name Synonym

Serine/arginine-rich splicing factor 7

Subcellular Location

Nucleus

Protein Name

Serine/arginine-rich splicing factor 7

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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