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Anti-CHD1L Antibody

Boster Bio Anti-CHD1L Antibody catalog # A05749. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Chromodomain-helicase-DNA-binding protein 1-like;3.6.4.12; Amplified in liver cancer protein 1; CHD1L; ALC1

Gene Name

CHD1L

UniProt

Q86WJ1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CHD1L. AA range:545-594

Clonality

Polyclonal

Tissue Specificity

Frequently overexpressed in hepatomacellular carcinomas. .

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly (ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly (ADP-ribose) -binding. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

100984 MW

Gene Name Synonym

Chromodomain-helicase-DNA-binding protein 1-like

Subcellular Location

Nucleus . Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1.

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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