Anti-REG3A Antibody (C-term)
Boster Bio Anti-REG3A Antibody (C-term) (Catalog # A05686-2) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
Synonyms
Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1
Gene Name
REG3A
UniProt
Q06141
Host
Rabbit
Reactivity
Human
Immunogen
This REG3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 129-163 amino acids from the C-terminal region of human REG3A.
Clonality
Polyclonal
Tissue Specificity
Expressed by keratinocytes (PubMed:27830702) . Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level) (PubMed:22727489) . Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis (PubMed:1469087) .
Applications
Flow Cytometry, WB
Field of Research
Cancer, Inflammation, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
1693176224256734
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
19395 Da
Subcellular Location
Secreted. Note=Found in the apical region of pancreatic acinar cells
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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