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Anti-REG3A Antibody

Boster Bio Anti-REG3A Antibody (Catalog# A05686) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Regenerating islet-derived protein 3-alpha; REG-3-alpha; Hepatointestinal pancreatic protein; HIP/PAP; Human proislet peptide; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-alpha; Reg III-alpha; Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form; REG3A; HIP, PAP, PAP1

Gene Name

REG3A

UniProt

Q06141

Host

Rabbit

Reactivity

Human

Immunogen

A full length recombinant REG3A protein

Clonality

Polyclonal

Tissue Specificity

Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level) . Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.

Applications

WB

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

19395 MW

Applications Notes

Western blot: 0.1-0.5 μg/ml

Gene Name Synonym

Regenerating islet-derived protein 3-alpha

Subcellular Location

Secreted. Found in the apical region of pancreatic acinar cells.

Protein Name

Regenerating islet-derived protein 3-alpha

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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