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Anti-ADAM22 Antibody

Boster Bio Anti-ADAM22 Antibody catalog # A05660. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Disintegrin and metalloproteinase domain-containing protein 22; ADAM 22; Metalloproteinase-disintegrin ADAM22-3; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2; ADAM22; MDC2

Gene Name

ADAM22

UniProt

Q9P0K1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human ADAM22 (NP_004185.1) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein (PubMed:19692335) . Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

100433 MW

Applications Notes

WB: 1:1000-1:4000

Gene Name Synonym

Disintegrin and metalloproteinase domain-containing protein 22

Subcellular Location

Cell membrane

Protein Name

Disintegrin and metalloproteinase domain-containing protein 22

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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