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Anti-Plakophilin 4 PKP4 Antibody

Boster Bio Anti-Plakophilin 4 PKP4 Antibody catalog # A05639. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Plakophilin-4; p0071; PKP4

Gene Name

PKP4

UniProt

Q99569

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human PKP4. AA range:185-234

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

131868 MW

Gene Name Synonym

Plakophilin-4

Subcellular Location

Cell junction, desmosome . Cytoplasm, cytoskeleton, spindle . Midbody . Cell membrane ; Peripheral membrane protein . Associated with the pericentrosomal region in interphase and with spindle poles during mitosis. In anaphase, during chromosome segregation, is recruited to the central microtubule bundle, focussed at the spindle midzone and ultimately localizes to the midbody at cytokinesis. Constituent of the midbody cytoskeletal matrix. Colocalized with desmoplakin at desmosomal junctional plaques in cultured epithelial cells.

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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