Anti-MED13L Antibody
Boster Bio Anti-MED13L Antibody catalog # A05593. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Mediator of RNA polymerase II transcription subunit 13-like; Mediator complex subunit 13-like; Thyroid hormone receptor-associated protein 2; Thyroid hormone receptor-associated protein complex 240 kDa component-like; MED13L; KIAA1025, PROSIT240, THRAP2, TRAP240L
Gene Name
MED13L
UniProt
Q71F56
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding Human MED13L.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain (cerebellum), heart (aorta), skeletal muscle, kidney, placenta and peripheral blood leukocytes. Highly expressed in fetal brain.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
242602 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Mediator of RNA polymerase II transcription subunit 13-like
Subcellular Location
Nucleus .
Protein Name
Mediator of RNA polymerase II transcription subunit 13-like
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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