Anti-STEAP3 Antibody
Boster Bio Anti-STEAP3 Antibody catalog # A05568-2. Tested in WB, IHC, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
STEAP3 (Six-Transmembrane Epithelial Antigen of Prostate 3) is also named as TSAP6, Dudulin-2 and pHyde, and belongs to the STEAP family. STEAP3 is a member of the STEAP family and is composed of a six-transmembrane domain at the COOH-terminal domain and a cytoplasmic N-terminal oxidoreductase domain, which is essential for iron and copper uptake (PMID:16227996) . STEAP3 contains a functional p53-binding site in its promoter and can be upregulated following p53 activation to enhance cell death in myeloid leukemia cell line and breast cancer cells (PMID: 18617898) . By interacting with Nix, a pro-apoptotic Bcl-2 family member, and Myt1 kinase, a negative regulator of the G2/M transition, STEAP3 overexpression promotes apoptosis and inhibits G2/M transition in cell cycle progression (PMID: 12606722, PMID: 10504341) .
Gene Name
STEAP3
UniProt
Q658P3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human STEAP3 recombinant protein (Position: K62-E127) .
Clonality
Polyclonal
Applications
WB, IHC, ICC/IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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