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Anti-JMY Antibody

Boster Bio Anti-JMY Antibody catalog # A05423-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Junction mediating and regulatory protein (JMY) is a 988 amino acid protein, which contains one WH2 domain and belongs to the JMY family. IIn nucleus, JMY acts both a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics in response to cellular stress. In cytoplasm, JMY acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Due to alternative splicing, several isoforms of JMY are produced, and these various isoforms have different influencing affects on p53 activation, with some isoforms markedly enhancing p53 responses compared to the other splicing variants.

Synonyms

WHDC1L3; Junction-mediating and -regulatory protein

Gene Name

JMY

UniProt

Q8N9B5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human JMY recombinant protein (Position: L714-W986) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Gene Name Synonym

Junction mediating and regulatory protein, p53 cofactor

Protein Name

Junction-mediating and -regulatory protein

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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