Anti-CRSP77 (V171) MED17 Antibody
Boster Bio Anti-CRSP77 (V171) MED17 Antibody catalog # A05399. Tested in IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Mediator of RNA polymerase II transcription subunit 17; Activator-recruited cofactor 77 kDa component; ARC77; Cofactor required for Sp1 transcriptional activation subunit 6; CRSP complex subunit 6; Mediator complex subunit 17; Thyroid hormone receptor-associated protein complex 80 kDa component; Trap80; Transcriptional coactivator CRSP77; Vitamin D3 receptor-interacting protein complex 80 kDa component; DRIP80; MED17; ARC77, CRSP6, DRIP77, DRIP80, TRAP80
Gene Name
MED17
UniProt
Q9NVC6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 140-190 of Human CRSP77.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
72890 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Mediator of RNA polymerase II transcription subunit 17
Subcellular Location
Nucleus .
Protein Name
Mediator of RNA polymerase II transcription subunit 17
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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