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Anti-CysLTR1/Cyslt1 Antibody

Boster Bio Anti-CysLTR1/Cyslt1 Antibody catalog # A05393. Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cysteinyl leukotriene receptor 1; CysLTR1; Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81; CYSLTR1; CYSLT1

Gene Name

CYSLTR1

UniProt

Q9Y271

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human CYSLTR1. AA range:131-180

Tissue Specificity

Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.

Applications

WB, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

38541 MW

Gene Name Synonym

Cysteinyl leukotriene receptor 1

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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