Anti-Frequenin Ncs1 Antibody
Boster Bio Anti-Frequenin Ncs1 Antibody (Catalog # A05330) . Tested in IF applications. This antibody reacts with Mouse.
Product Specifications
Background
Frequenin, or Neuronal calcium sensor, is a regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. It directly regulates GRK1 (RHOK), but not GRK2 to GRK5. It can substitute for calmodulin and it stimulates PI4KB kinase activity. It is involved in long-term synaptic plasticity through its interaction with PICK1. Ncs1 may also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
Synonyms
FREQUENIN, NCS-1, FLUP, FREQ, Neuronal calcium sensor 1, frequenin homolog, Frequenin-like protein, NCS 1, NCS1
Gene Name
NCS1
UniProt
Q8BNY6
Host
Rabbit
Reactivity
Mouse
Immunogen
Frequenin (recombinant from Mouse with extensive post-translational modifications)
Clonality
Polyclonal
Applications
ELISA, IF, WB
Field of Research
Calcium Binding Proteins, Calcium Signaling, Neuroscience, Neurotransmission
Purification
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Frequenin (recombinant) coupled to agarose beads. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
Concentration
2.0 mg/mL by UV absorbance at 280 nm
Form
Liquid (sterile filtered)
Shipping Conditions
Dry Ice Shipping
Storage Conditions
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening. (Ship on dry ice.)
Isotype
IgG
Contents
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
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