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Anti-VAPA Antibody

Boster Bio Anti-VAPA Antibody catalog # A05329. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Vesicle-associated membrane protein-associated protein A; VAMP-A; VAMP-associated protein A; VAP-A;33 kDa VAMP-associated protein; VAP-33; VAPA; VAP33

Gene Name

VAPA

UniProt

Q9P0L0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human VAPA (NP_919415.2) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204) . The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204) . With OSBPL3, may regulate ER morphology (PubMed:16143324) . May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

27893 MW

Gene Name Synonym

Vesicle-associated membrane protein-associated protein A

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Vesicle-associated membrane protein-associated protein A

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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