Anti-PLOD1 Antibody
Boster Bio Anti-PLOD1 Antibody catalog # A05322. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1;1.14.11.4
Gene Name
PLOD1
UniProt
Q02809
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PLOD1 (NP_000293.2) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity) . Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (PubMed:8621606, PubMed:10686424, PubMed:15854030) . These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
83550 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Subcellular Location
Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein Name
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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