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Anti-PLOD1 Antibody

Boster Bio Anti-PLOD1 Antibody catalog # A05322. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1;1.14.11.4

Gene Name

PLOD1

UniProt

Q02809

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PLOD1 (NP_000293.2) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity) . Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (PubMed:8621606, PubMed:10686424, PubMed:15854030) . These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

83550 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

Subcellular Location

Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.

Protein Name

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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