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Anti-CHRNA9 Antibody (N-term)

Boster Bio Anti-CHRNA9 Antibody (N-term) (Catalog # A05280-1) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.

Synonyms

Neuronal acetylcholine receptor subunit alpha-9, Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9, CHRNA9, NACHRA9

Gene Name

CHRNA9

UniProt

Q9UGM1

Host

Rabbit

Reactivity

Human

Immunogen

This CHRNA9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 8-42 amino acids from the N-terminal region of human CHRNA9.

Clonality

Polyclonal

Tissue Specificity

Expressed in cochlea, keratinocytes, pituitary gland, B-cells and T-cells.

Applications

Flow Cytometry, WB

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

1175221625282151117522162528215111021840

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

54807 Da

Subcellular Location

Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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