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Anti-Zinc finger protein Helios IKZF2 Antibody

Boster Bio Anti-Zinc finger protein Helios IKZF2 Antibody (Catalog # A05228) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The Ikaros family zinc finger 2 (IKZF2) is a member of the Ikaros family of zinc-finger proteins, a family of hematopoietic-specific transcription factors involved in the regulation of lymphocyte development (1,2) . IKZF2 forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development (3) . Its expression is a marker for T cell activation and proliferation (4) .

Synonyms

Ikaros family zinc finger 2 (Helios), ANF1A2, HELIOS, ZNF1A2, ZNFN1A2

Gene Name

IKZF2

UniProt

Q9UKS7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

IKZF2 antibody is human, mouse and rat reactive. At least two isoforms of IKZF2 are known to exist; this antibody will detect both isoforms. IKZF2 antibody is predicted to not cross-react with other IKZF proteins.

Immunogen

IKZF2 antibody was raised against a 19 amino acid peptide near the amino terminus of human IKZF2. The immunogen is located within amino acids 50 - 100 of IKZF2.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Stem Cells, Immunology

Purification

IKZF2 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Associates with Ikaros at centromeric heterochromatin.

Storage Conditions

IKZF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

59574 MW

Gene Name Synonym

Ikaros family zinc finger 2 (Helios)

Subcellular Location

Nucleus .

Protein Name

Ikaros family zinc finger 2 (Helios)

Isotype

IgG

Contents

IKZF2 antibody is supplied in PBS containing 0.02% sodium azide.

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