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Anti-MMP-19 (G44) Antibody

Boster Bio Anti-MMP-19 (G44) Antibody catalog # A05171. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Matrix metalloproteinase-19; MMP-19;3.4.24.-; Matrix metalloproteinase RASI; Matrix metalloproteinase-18; MMP-18; MMP19; MMP18, RASI

Gene Name

MMP19

UniProt

Q99542

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 12-60 of Human MMP-19.

Clonality

Polyclonal

Tissue Specificity

Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients (PubMed:8920941) .

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease) . May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

57357 MW

Applications Notes

IHC: 1:50-1:200

Gene Name Synonym

Matrix metalloproteinase-19

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Protein Name

Matrix metalloproteinase-19

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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