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Anti-SNX3 Antibody (Center)

Boster Bio Anti-SNX3 Antibody (Center) (Catalog # A05169-2) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.

Synonyms

Sorting nexin-3, Protein SDP3, SNX3

Gene Name

SNX3

UniProt

O60493

Host

Rabbit

Reactivity

Human

Immunogen

This SNX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-105 amino acids from the Central region of human SNX3.

Clonality

Polyclonal

Applications

IHC-P, WB

Field of Research

Signal Transduction, Viral process

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

2172531924344282302139402323708020482551

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

18762 Da

Subcellular Location

Early endosome. Cytoplasmic vesicle, phagosome. Note=Colocalizes to clathrin-coated endosomal vesicles morphologically distinct from retromer-decorated non-branched endosomal tubule structures (PubMed:21725319) Colocalizes with EEA1 on nascent phagosomes in dendritic cells but competes with EEA1 for binding to phagosomal membrane (PubMed:23237080) . In the case of Salmonella enterica infection localizes to Salmonella-containing vacuoles (SCVs) from which SNX3-containing tubules form 30-60 min after infection (PubMed:20482551) .

Prediction Reactivity

Bovine, Rat

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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