Anti-SRGAP2 Antibody
Boster Bio Anti-SRGAP2 Antibody catalog # A05125-1. Tested in WB, IHC, IP, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
SLIT-ROBO Rho GTPase-activating protein 2 (SRGAP2) is also named as ARHGAP34, FNBP2, KIAA0456 and SRGAP2A. SRGAP2 plays important roles in axon guidance, neuronal migration, synapse formation, and nerve regeneration. SRGAP2 protein was first expressed in the retina of normal mice at the embryonic stage and was mainly located in the mature retinal ganglion cell layer and the inner nuclear layer (PMID: 37056152) . SRGAP2 plays a key role in neuronal morphogenesis and migration mainly during development of the cerebral cortex (PMID: 20810653, PMID: 27373832, PMID: 28333212) . SRGAP2 are critical for neuronal migration through inactivation of Rho GTPases Cdc42, Rac1, and RhoA (PMID: 20810653) . SRGAP2A promotes synaptic maturation, and ultimately the synaptic accumulation of AMPA and GABAA receptors, by interacting with key components of both excitatory and inhibitory postsynaptic scaffolds, Homer and Gephyrin (PMID: 27373832) .
Synonyms
SRGAP2A; SLIT-ROBO Rho GTPase-activating protein 2; Rho GTPase-activating protein 34; Formin-binding protein 2; FNBP2
Gene Name
SRGAP2
UniProt
O75044
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human SRGAP2 recombinant protein (Position: D786-I942) .
Clonality
Polyclonal
Applications
WB, IHC, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
SLIT-ROBO Rho GTPase activating protein 2
Protein Name
SLIT-ROBO Rho GTPase-activating protein 2
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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