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Anti-TAB3/Map3K7Ip3 Antibody

Boster Bio Anti-TAB3/Map3K7Ip3 Antibody (Catalog# A05084) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Mitogen-activated protein kinase kinase kinase 7-interacting protein 3; NF-kappa-B-activating protein 1; TAK1-binding protein 3; TAB-3; TGF-beta-activated kinase 1-binding protein 3; TAB3; MAP3K7IP3

Gene Name

TAB3

UniProt

Q8N5C8

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant TAB3 protein (amino acids 1-350)

Clonality

Polyclonal

Tissue Specificity

Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, MAPK Pathway, NFKB Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Signaling Pathway, TLR Signaling

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

78683 MW

Applications Notes

Western blot: 4-6 μg/ml

Gene Name Synonym

TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

Protein Name

TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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