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Anti-HIP1R Antibody

Boster Bio Anti-HIP1R Antibody catalog # A05059. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Huntingtin-interacting protein 1-related protein; HIP1-related protein; Huntingtin-interacting protein 12; HIP-12; HIP1R; HIP12, KIAA0655

Gene Name

HIP1R

UniProt

O75146

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human HIP1R (NP_003950.1) .

Clonality

Polyclonal

Tissue Specificity

Brain, heart, kidney, pancreas, and liver, but not in lung or placenta.

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

119388 MW

Gene Name Synonym

Huntingtin-interacting protein 1-related protein

Subcellular Location

Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.

Protein Name

Huntingtin-interacting protein 1-related protein

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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