Anti-MAGED1 Antibody
Boster Bio Anti-MAGED1 Antibody catalog # A05037-1. Tested in WB, IHC, ICC, IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
MAGED1 (also known as NRAGE or Dlxin-1) is a member of the type II melanoma antigen (MAGE) family of protein. MAGED1 can interact with the nerve growth factor receptor p75NTR, antagonize the association of p75NTR with TrkA, inhibit cell cycle progression, and facilitate p75NTR-mediated apoptosis (PMID: 10985348) . It has been reported that MAGED1 binds Dlx5 and regulates its transcriptional function. In vivo, MAGED1 binds not only Dlx5 but also Dlx7 and Msx2 and forms homomultimers (PMID: 11084035) . MAGED1 knockout mice show depressive behavior and impairments of circadian rhythm (PMID: 20300063; 23314527) . Three transcript variants encoding two different isoforms (86kDa and 92 kDa) have been found for the gene of MAGED1.
Synonyms
PP2250; NRAGE; Neurotrophin receptor-interacting MAGE homolog; Melanoma-associated antigen D1; MAGE-D1 antigen
Gene Name
MAGED1
UniProt
Q9Y5V3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human MAGED1 recombinant protein (Position: Q3-P344) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, Flow Cytometry, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
MAGE family member D1
Protein Name
Melanoma-associated antigen D1
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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