Anti-KANK1 Antibody
Boster Bio Anti-KANK1 Antibody catalog # A05029-1. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
KANK1 (KN motif and ankyrin repeat domain-containing protein 1) is involved in the control of cytoskeleton formation by regulating actin polymerization, inhibiting actin fiber formation and cell migration (PMID: 25961457) . It inhibits RhoA activity, the formation of lamellipodia but not of filopodia (PMID: 25961457, PMID: 5961457) .It also inhibits fibronectin-mediated cell spreading and regulates Rac signaling pathways (PMID: 25961457) . Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions (PMID: 27410476) . KANK1 can be detected 130-200 kDa (PMID: 15823577, PMID: 33253712, PMID: 35805114) .
Synonyms
KN motif and ankyrin repeat domain-containing protein 1; Kidney ankyrin repeat-containing protein; KIAA0172; KANK; Ankyrin repeat domain-containing protein 15
Gene Name
KANK1
UniProt
Q14678
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human KANK1 recombinant protein (Position: V293-L465) .
Clonality
Polyclonal
Applications
WB, IHC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
KN motif and ankyrin repeat domains 1
Protein Name
KN motif and ankyrin repeat domain-containing protein 1
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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