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Anti-Collagen alpha-1 (XII) chain COL12A1 Antibody

Boster Bio Anti-Collagen alpha-1 (XII) chain COL12A1 Antibody catalog # A05008. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Collagen alpha-1 (XII) chain; COL12A1; COL12A1L

Gene Name

COL12A1

UniProt

Q99715

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen XII alpha1. AA range:1481-1530

Clonality

Polyclonal

Tissue Specificity

Found in collagen I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine, and in cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, kidney and a squamous cell carcinoma cell line. Isoform 1 is also present in the corneal epithelial Bowman's membrane (BM) and the interfibrillar matrix of the corneal stroma, but it is not detected in the limbal BM.

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

333147 MW

Gene Name Synonym

Collagen alpha-1 (XII) chain

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Protein Name

Collagen alpha-1 (XII) chain

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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